 Seven of Lords#42982 · Quest items | 1 | — | No equipment slot | Rare |
 Seven of Prisms#44266 · Quest items | 1 | — | No equipment slot | Rare |
 Seven of Chaos#44284 · Quest items | 1 | — | No equipment slot | Rare |
 Seven of Undeath#44292 · Quest items | 1 | — | No equipment slot | Rare |
 Seven-Fingered Claws#50315 · Weapons | 232 | 80 | Main hand | Epic |
 Seventh Ring of the Tirisfalen#30028 · Armor | 128 | 70 | Finger | Epic |
 Fey Dragon Scale#5583 · Quest items | 1 | — | No equipment slot | Common |
 Dust of the Fey Drake#30174 · Quest items | 1 | — | No equipment slot | Common |
 Withered Basidium#24483 · Quest items | 1 | 60 | No equipment slot | Common |
| Withered Basidium#24484 · Quest items | 1 | 60 | No equipment slot | Common |
 Faceless One's Withered Brain#43821 · Quest items | 1 | — | No equipment slot | Common |
 Feyscale Cloak#6632 · Armor | 20 | 15 | Back | Rare |
 Venomtail Antidote#4904 · Quest items | 1 | — | No equipment slot | Common |
 Lingering Illness#50063 · Armor | 264 | 80 | Waist | Epic |
| Lingering Illness#50702 · Armor | 277 | 80 | Waist | Epic |
 Blood Boil Lancet#49790 · Weapons | 219 | 80 | Two-hand | Epic |
 Seethe#50210 · Weapons | 232 | 80 | Main hand | Epic |
 Settler's Leggings#2694 · Armor | 17 | — | Legs | Uncommon |
 NPC Equip 35853#35853 · Quest items | 0 | — | No equipment slot | Poor |
 Sigil of Deflection#45144 · Armor | 226 | 80 | Relic | Epic |
| Sigil of Insolence#47672 · Armor | 245 | 80 | Relic | Epic |
 Signet of Beckoning: Thunder#20433 · Quest items | 1 | — | No equipment slot | Common |
| Signet of Beckoning: Fire#20432 · Quest items | 1 | — | No equipment slot | Common |
| Signet of Beckoning: Stone#20435 · Quest items | 1 | — | No equipment slot | Common |
| Signet of Beckoning: Water#20436 · Quest items | 1 | — | No equipment slot | Common |
| Sigil of Arthritic Binding#40875 · Armor | 150 | 74 | Relic | Rare |
 Signet of the Malevolent#39389 · Armor | 200 | 80 | Finger | Epic |
 Seal of the Dawn#13209 · Armor | 61 | — | Trinket | Rare |
 Signet of the Dark Brotherhood#38675 · Armor | 70 | — | Trinket | Rare |
 Signet of Repose#27491 · Armor | 115 | 70 | Finger | Rare |