 Searing Golden Blade#12260 · Weapons | 39 | 34 | Main hand | Uncommon |
 Searing Sunblade#29275 · Weapons | 110 | 70 | Off hand | Epic |
 Scorch Wood Bow#31416 · Weapons | 108 | — | Ranged | Uncommon |
 Searing Blade#12992 · Weapons | 23 | 18 | Two-hand | Rare |
 Searing Needle#12531 · Weapons | 51 | 46 | One-hand | Rare |
 Scythe of the Unseen Path#21401 · Weapons | 70 | 60 | One-hand | Epic |
 Scythe Axe#5749 · Weapons | 23 | 18 | Two-hand | Uncommon |
 Seraph's Strike#5614 · Weapons | 31 | — | Two-hand | Uncommon |
 Serathil#13015 · Weapons | 61 | 56 | One-hand | Rare |
 Serilas, Blood Blade of Invar One-Arm#45947 · Weapons | 232 | 80 | One-hand | Epic |
 Serpentine Skuller#12605 · Weapons | 56 | 51 | Ranged | Rare |
 Servomechanic Sledgehammer#4548 · Weapons | 41 | — | Two-hand | Uncommon |
 Seth's Graphite Fishing Pole#25978 · Weapons | 60 | — | Two-hand | Uncommon |
 Plaguerot Sprig#10766 · Weapons | 40 | 35 | Ranged | Rare |
 Plague Igniter#40284 · Weapons | 213 | 80 | Ranged | Epic |
 Severin's Cane#32830 · Weapons | 109 | — | Two-hand | Rare |
 Olmann Sewar#4116 · Weapons | 41 | — | One-hand | Uncommon |
 Shaarde the Lesser#25964 · Weapons | 100 | 65 | One-hand | Rare |
 Shaarde the Greater#25944 · Weapons | 97 | 64 | Two-hand | Rare |
 NPC Equip 50257#50257 · Weapons | 0 | — | One-hand | Poor |
 NPC Equip 50251#50251 · Weapons | 0 | — | Off hand | Poor |
| NPC Equip 50256#50256 · Weapons | 0 | — | One-hand | Poor |
| Shadowmourne Monster Offhand#50815 · Weapons | 132 | 70 | One-hand | Epic |
 Shani's Crysknife#31759 · Weapons | 94 | — | One-hand | Rare |
 Shekketh Talons#25187 · Weapons | 90 | 60 | Off hand | Uncommon |
 Shoni's Disarming Tool#9608 · Weapons | 31 | — | Off hand | Uncommon |
 Shuriken of Negation#28826 · Weapons | 125 | 70 | Thrown | Epic |
 Serpentshrine Shuriken#30025 · Weapons | 134 | 70 | Thrown | Epic |
| Crescent of Forlorn Spirits#2044 · Weapons | 35 | — | One-hand | Rare |
| Sickle of Unyielding Strength#21392 · Weapons | 70 | 60 | One-hand | Epic |