 Shivering Felspine#34183 · Weapons | 154 | 70 | Two-hand | Epic |
 Splintershard#51784 · Weapons | 251 | 80 | Off hand | Epic |
| Splintershard#51819 · Weapons | 264 | 80 | Off hand | Epic |
 Stonesplinter Axe#2265 · Weapons | 13 | 8 | One-hand | Uncommon |
 Stonesplinter Dagger#2266 · Weapons | 13 | 8 | One-hand | Uncommon |
 Stonesplinter Blade#2268 · Weapons | 10 | 5 | Main hand | Common |
 Stonesplinter Rags#5109 · Armor | 17 | 12 | Chest | Common |
 Stonesplinter Mace#2267 · Weapons | 15 | 10 | One-hand | Uncommon |
 Shardtooth Meat#12622 · Quest items | 1 | — | No equipment slot | Common |
 Spojka Rich Purple Shirt#27007 · Armor | 0 | — | Hands | Rare |
 Spojka Black Shirt#27002 · Armor | 0 | — | Shoulder | Rare |
 Sporeggar Mushroom#29453 · Consumables | 75 | 65 | No equipment slot | Common |
 Spore-covered Tunic#5341 · Armor | 15 | — | Chest | Uncommon |
 Sporid Cape#6629 · Armor | 23 | 18 | Back | Rare |
 Sporebat Eye#24426 · Quest items | 1 | — | No equipment slot | Common |
 Steaming Fungus#39550 · Miscellaneous | 1 | — | No equipment slot | Poor |
 Spore-Soaked Vaneer#24362 · Armor | 91 | 62 | Back | Rare |
 Spored Tendrils Spaulders#35616 · Armor | 167 | 73 | Shoulder | Rare |
 Sporeling Claw#25538 · Weapons | 94 | — | One-hand | Rare |
 Sporeling Snack#27656 · Consumables | 65 | 55 | No equipment slot | Common |
 Coilfang Needler#24381 · Weapons | 91 | 62 | Ranged | Rare |
 Spur Ring#36429 · Armor | 178 | 79 | Finger | Uncommon |
 Sporting Rifle#25277 · Weapons | 108 | 66 | Ranged | Uncommon |
 Spraggle's Canteen#11804 · Quest items | 1 | — | No equipment slot | Common |
| Spraggle's Canteen#15722 · Quest items | 1 | — | No equipment slot | Common |
 Explosive Charges#39165 · Quest items | 70 | 74 | No equipment slot | Common |
 Skyguard Blasting Charges#32406 · Consumables | 0 | — | No equipment slot | Common |
| Venture Co. Explosives#39651 · Quest items | 1 | — | No equipment slot | Common |
 Pack of Nozzlerust Explosives#37922 · Quest items | 1 | — | No equipment slot | Common |
 Sprouted Frond#5205 · Consumables | 15 | 5 | No equipment slot | Common |